Sesame Seed Extract
Sesame Seed Extract - Premium natural ingredient from GEM Nature Nutrition
| 规格名称 | 规格值 |
|---|---|
| Active Ingredients | Sesamin; Sesamolin |
| Sesamin CAS NO. | 607-80-7 |
| Sesamolin CAS NO. | 526-07-8 |
| Shelf Life | 24 months |
| Solvents | Water and ethanol |
Sesame Seed Extract
Sesame Seeds Extract Details Quick View
Specification: 5%-99% by HPLC
Mesh: 40mesh
Certificate: ISO22000; ISO14001; ISO9001; GMP; Kosher; Halal
Annual Production Capacity: More than 20 tons
Features: Fine powder; Non-GMO; Non-ETO; Non-Radiation; USP&EP Standard; Allergen (soy, gluten) free; Super antioxidant&radio-resistance.
Application: Pharmaceutical and medicine; Dietary supplement; Basic nutritional ingredients; Food and beverages; Food additives and Cosmetics; Feed and pet industry. etc.
Main function: Antioxidant, Anti-inflammatory, Liver protection, and Cholesterol management
What is Sesame Seed Extract?
Sesame Seed Extract is a concentrated form of the bioactive compounds found in Sesamum indicum (sesame seeds), we call it "Zhi Ma" in Chinese. While sesame seeds are a staple in global diets, the medicinal power lies in a specific class of polyphenols called Lignans. Our extract is standardized to provide high concentrations of Sesamin and Sesamolin, the two most potent lignans for human metabolic support.
1. The Core Actives: Sesamin & Sesamolin
Sesamin: The most abundant and researched lignan in sesame. It is a "super-antioxidant" that primarily targets liver health and lipid metabolism.
Sesamolin: A synergistic partner to Sesamin. Research shows that Sesamolin significantly enhances the body's ability to reduce oxidative stress and supports cardiovascular integrity.
2. Mechanism of Action: How it Works in the Body
Unlike general antioxidants, Sesame Seed Extract has a targeted "Fat-Burning" effect at the cellular level:
- Hepatic Fatty Acid Oxidation: Sesamin acts as a potent inducer of liver enzymes. It increases the rate at which the liver breaks down fatty acids for energy (oxidation).
- Lipid Regulation: By accelerating fat oxidation, our lignan-rich extract helps lower serum triacylglycerol (triglyceride) levels, promoting a healthier blood lipid profile and reducing the risk of fatty liver accumulation.
Sesame Seeds Extract Specification
| Test Item | Specification | Method |
|---|---|---|
| Sesamin assay | ≥ 90.0 | HPLC |
| Identification | Positive | TLC |
| Appearance | Off white powder | Visual |
| Odor | Characteristic | Organoleptic |
| Powder Size | ≥ 95% through 40 mesh | USP #40 Sieve |
| Loss on Drying | ≤ 0.5% | USP-NF<731> |
| Residue on Ignition | ≤ 0.5% | USP-NF<281> |
| Residual Ethanol | ≤ 5,000 μg/g | USP-NF<467> |
| Pesticide Residues | USP<561> | USP-NF<561> |
| Aflatoxin B1 | ≤2 μg/kg | USP-NF<561> |
| Aflatoxins(B1,B2,G1,G2) | ≤4 μg/kg | USP-NF<561> |
| Total Heavy Metals | ≤ 10 μg/g | USP-NF<231> |
| Arsenic (As) | ≤ 1.0 μg/g | ICP-MS |
| Cadmium (Cd) | ≤ 0.5 μg/g | ICP-MS |
| Lead (Pb) | ≤ 1.0 μg/g | ICP-MS |
| Mercury (Hg) | ≤ 0.1 μg/g | ICP-MS |
| Total Plate Count | ≤ 1,000 cfu/g | USP-NF<2021> |
| Molds and Yeasts | ≤ 100 cfu/g | USP-NF<2021> |
| Salmonella | Absence/10g | USP-NF<2022> |
| E. Coli | Absence/10g | USP-NF<2022> |
| Staphylococcus aureus | Absence/10g | USP-NF<2022> |
Production Process
Sesame seeds→Extraction→Concentration→Coarse crystallization→Centrifugation→Dissolve→Decolorization→Crystallization→Centrifugation→Drying→Sieving&Mixing→Metal detection→Packing→Finished products.
What's the main function of sesame seeds extract?
Sesame Seed Extract is a bioactive powerhouse known for its high concentration of lignans. Unlike standard sesame oil, our standardized extract delivers concentrated Sesamin, providing therapeutic benefits for the liver, bones, and cardiovascular system.
1. Superior Antioxidant Capacity
Sesame Seed Extract acts as a high-efficiency scavenger of harmful free radicals. Its performance in laboratory tests is often compared to Vitamin C (VC).
- Free Radical Neutralization: Sesamin effectively removes excessive peroxides, hydroxyl radicals, and organic radicals from the body.
- Mechanism: It increases the activity of endogenous scavenging enzymes, inhibiting oxidative stress and protecting target organs from cellular damage.
- Skin Protection: Research indicates that this potent antioxidant activity provides a layer of defense against oxidative damage linked to skin cancer.
2. Powerful Anti-Inflammatory & Bone Support
Recent research highlights Sesamin as a breakthrough for inflammatory bone conditions.
- Inhibiting Bone Resorption: Sesamin prevents the over-differentiation of osteoclasts (cells that break down bone tissue), which helps maintain bone density.
- Signaling Pathways: It works by suppressing the ERK and NF-κB signaling pathways, reducing the production of pro-inflammatory cytokines.
- Therapeutic Potential: These properties make it a promising natural ingredient for treating inflammatory bone loss and LPS-induced osteolysis.
3. Comprehensive Liver Protection & Detoxification
The liver is the primary site for Sesamin metabolism, making it a highly effective "liver-targeted" supplement.
- Alcohol Metabolism: Sesamin regulates enzymes involved in ethanol breakdown, accelerating the clearance of alcohol and reducing liver damage.
- Fatty Liver Prevention: By enhancing the β-oxidation of fatty acids, it prevents the accumulation of fat in the liver, supporting long-term hepatic health and preventing non-alcoholic fatty liver issues.
4. Natural Cholesterol Management
Clinical trials have proven that Sesame Seed Extract is a safe, side-effect-free alternative to traditional lipid-lowering agents.
- The Study: In trials with hypercholesterolemia patients, standardized sesame extract achieved the following results:
- 8.5% Decrease in total serum cholesterol
- 14% Decrease in "Bad" Cholesterol (LDL-C)
- 4% Increase in "Good" Cholesterol (HDL-C)
- The Benefit: It provides pharmaceutical-grade lipid regulation without the common side effects associated with synthetic drugs.
